The actor, who is now 24, held nothing back in an interview with the , saying: "I had a really, really hard time working with Aniston because I was so in love with her".
"I was infatuated," he continued. "I was speechless — I’d get all bubbly and forget my lines and completely blank. It was so difficult".
Sprouse played the role of Ben from 2000 to 2002, starting when he was just eight-years-old. He then went on to find success starring in The Suite Life Of Zack And Cody with his twin brother Dylan.
Talking about whether he has stayed in touch with any of the Friends cast, Sprouse said: "If I saw any of them, I’d say, 'Hello.' But it’s been a while and I certainly don’t look the same, so it’d be a hard sell. And if I did look the same, that’d be a little disconcerting."
We wonder what Jennifer makes of this declaration...
Scroll down to see pictures of Cole graduating with his brother Dylan:
Celebrity Graduation Snaps